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Avelox (moxifloxacin hydrochloride)


What is Avelox

Avelox or Moxifloxacin is approved by the Food and Drug Administration for use in the United States for the treatment of most bacterial infections. This drug should be used only if all other antibiotics fail. According to the pharmacokinetic data, Avelox has a bioavailability of 86-92%, and 40% protein binding on average. Avelox also has a half life of 12 hours in the body, metabolized by glucironide and sulfate conjugation and excreted in the feces.

Avelox was launched in United States in 1999 and is now available in more than 100 countries worldwide. Some restrictions were made in 2008-2009 due to some of Avelox's side effects. The Food and Drug Administration also issued warnings regarding some life-threatening reactions, such as tendon ruptures and breathing problems

How to use Medicine

It's necessary to drink more water if you are taking Avelox. Avelox should be taken only by prescription from a licensed doctor and do no longer than prescribed. Avelox can be taken with or without the food. If you skip a dose, it is more likely for that the infection will increase, and symptoms will improve if Avelox is taken always at the prescribed time. Many people think that it cures viral infections. This is a bad idea for self-medication, and Avelox does not cure viral infections.

Precautions and Contraindications

Avelox has some restrictions on its use, and can cause some serious effects. Avelox should not be used if you have any of the diseases mentioned below, or the history of them: myasthenia gravis, allergic to moxifloxacin, allergic to ofloxacin, allergic to norfloxacin.
Inform you doctor if you have the following conditions, so that he or she can make the correct decision whether to prescribe Avelox or not. These are: liver disease, kidney disease, arrhythmia, breathing trouble, muscle weakness, epilepsy, hypokalemia, long QT syndrome.
According to the Food and Drug Administration, the pregnancy category of Avelox is Category C. The exact effects of Avelox on the fetus are unknown. It's advisable to inform the doctor if you are pregnant or are planning to be pregnant before taking Avelox. The effect of Avelox on breast milk and breastfeeding is also unknown. It's advisable not to breast feed if you are using this drug.
There are chances of Avelox causing swelling or tendon rupture. Tendons are fibers connecting bones and muscles. The swelling is most often caused in the heel and particularly in patients above 60. If you have lung disease, liver problems, kidney problems, or transplanted organs, stop taking Avelox and consulting a doctor immediately if swelling occurs. Keep the swellingstationary.

Drug Interactions

Do not take Avelox if you are taking certain medicines, listed below. Taking both medicines may cause severe injury. These are: aluminum- and magnesium-containing antacids, carfate or any ulcer medicine, vitamin supplements with iron or zinc, didanosine.
Avelox causes you tos sunburn easily. It may cause itching or skin burns, and if they are severe please contact your doctor immediately. If you have any new infections while taking Avelox , you may acquire diarrhea. Do not take a medicine for diarrhea without consulting your doctor.

Side effects

The following are the most serious side effects of Avelox: Diarrhea, Sever headache, Pale skin, Infrequent urination, Easy bleeding, Swelling, Tenderness, Loss of movement in any of the joints, Skin rashes, Numbness, Severe skin reaction
Less serious side effects of Avelox are: mild headache, dizziness, nausea, mild diarrhea, blurred vision, feeling nervous.

400 mg

10, 15, 30, 60 pills

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